Pluripotency gene network dynamics: System views from parametric analysis
نویسندگان
چکیده
منابع مشابه
Concise review: the dynamics of induced pluripotency and its behavior captured in gene network motifs.
The flexibility of cellular identity is clearly demonstrated by the possibility to reprogram fully differentiated somatic cells to induced pluripotent stem (iPS) cells through forced expression of a set of transcription factors. The generation of iPS cells is of great interest as they provide a tremendous potential for regenerative medicine and an attractive platform to investigate pluripotency...
متن کاملEvolution of the mammalian embryonic pluripotency gene regulatory network.
Embryonic pluripotency in the mouse is established and maintained by a gene-regulatory network under the control of a core set of transcription factors that include octamer-binding protein 4 (Oct4; official name POU domain, class 5, transcription factor 1, Pou5f1), sex-determining region Y (SRY)-box containing gene 2 (Sox2), and homeobox protein Nanog. Although this network is largely conserved...
متن کاملanalysis of power in the network society
اندیشمندان و صاحب نظران علوم اجتماعی بر این باورند که مرحله تازه ای در تاریخ جوامع بشری اغاز شده است. ویژگیهای این جامعه نو را می توان پدیده هایی از جمله اقتصاد اطلاعاتی جهانی ، هندسه متغیر شبکه ای، فرهنگ مجاز واقعی ، توسعه حیرت انگیز فناوری های دیجیتال، خدمات پیوسته و نیز فشردگی زمان و مکان برشمرد. از سوی دیگر قدرت به عنوان موضوع اصلی علم سیاست جایگاه مهمی در روابط انسانی دارد، قدرت و بازتولید...
15 صفحه اولBifurcation analysis and dynamics of a Lorenz –type dynamical system
./files/site1/files/0Abstract1.pdfIn this paper we consider a continues Lorenz – type dynamical system. Dynamical behaviors of this system such as computing equilibrium points, different bifurcation curves and computation of normal form coefficient of each bifurcation point analytically and numerically. In particular we derived sufficient conditions for existence of Hopf and Pitchfork bifurcati...
متن کاملsystem dynamics approach for construction risk analysis
presence of risks and uncertainties inherent in project development and implementation playssignificant role in poor project performance. thus, there is a considerable need to have an effective riskanalysis approach in order to assess the impact of different risks on the project objectives. a powerful riskanalysis approach may consider dynamic nature of risks throughout the life cycle of the pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0194464